Anti-Paxillin (LD2 Motif) [LD2 sAB]

Absolute Antibody

Anti-Paxillin (LD2 Motif) [LD2 sAB]

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The antibody binds specifically to the LD-2 motif of human paxillin with a Kd of 24 nM.

This antibody binds to the LD2-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.

Western Blot, ELISA

ELISA; WB

Research Use Only

Monoclonal

LD2 sAB

PXN

paxillin

paxillin; testicular tissue protein Li 134

Mouse

IgG1

Paxillin

This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

Peptide corresponding to paxillin-LD2 motif (residues 141-156) fused to MBP; peptide sequence: NLSELDRLLLELNAVQHNP.

-20°C,2°C to 8°C

12352203