Anti-PD-1 [Anti-human PD-1 antibody]

Absolute Antibody

Anti-PD-1 [Anti-human PD-1 antibody]

9

The antibody is specific for PD-1. The antibody binds the extracellular region of the human PD-1 protein receptor. PD-1 is a type I membrane protein with 288 amino acids, and is one of the main known immune checkpoints. PD-1 is expressed in activated T ly

The specificity of the original format of the antibody was confirmed by ELISA analysis (EC50 = 76 pM). The antibody blocked the binding between PD-1 protein and its ligands PD-L1 and PD-L2 by the receptor ligand binding assay of PD-1 protein. Lymphocyte stimulation assay detected that PD-1 antibody blocked the binding of PD-1 protein to its ligands PD-L1 and PD-L2, thereby releasing its inhibition of T lymphocyte activity (CN106928361A).

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

Anti-human PD-1 antibody

PDCD1

programmed cell death 1

CD279; hPD-1; hPD-l; hSLE1; PD1; PD-1; programmed cell death 1 protein; programmed cell death protein 1; protein PD-1; SLEB2; systemic lupus erythematosus susceptibility 2

Human

IgG1

Programmed cell death protein 1

Human

-20°C,2°C to 8°C

12352203