anti-PDX1 antibody

Arigo Biolaboratories

anti-PDX1 antibody

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

PDX1

pancreatic and duodenal homeobox 1

glucose-sensitive factor; GSF; IDX-1; insulin promoter factor 1, homeodomain transcription factor; insulin upstream factor 1; IPF1; IPF-1; islet/duodenum homeobox-1; IUF1; IUF-1; MODY4; PAGEN1; pancreas/duodenum homeobox protein 1; pancreatic-duodenal homeobox factor 1; PDX-1; somatostatin transcription factor 1; somatostatin-transactivating factor 1; STF-1

Rabbit

IgG

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008]

Human

-20°C

12352203