Anti-PfRH5 [9AD4]

Absolute Antibody

Anti-PfRH5 [9AD4]

9

The antibody binds specifically to PfRH5, a member of the RH family of proteins of the Plasmodium falciparum which interacts with the surface protein basigin (CD147) of erythrocytes. The interaction between the two proteins is necessary for the parasitic invasion of erythrocytes, known to give rise to the pathology of malaria. The antibody 9AD4 inhibits parasitic growth, possibly by blocking the interaction of PfRH5 and another protein, or by blocking the processing of the PfRH5 protein.

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

9AD4

Rabbit

IgG

Reticulocyte binding protein 5

Plasmodium

-20°C,2°C to 8°C

12352203