Anti-Phosphorylatedtyrosine Antibody Conjugated Agarose Beads

PTM BIO

Anti-Phosphorylatedtyrosine Antibody Conjugated Agarose Beads

5

With a mixture of high-quality rabbit- and mouse-derived anti-Phosphorylatedtyrosine antibodies cross-linked, this Anti-Phosphorylatedtyrosine Antibody Conjugated Agarose Beads present extraordinary capability to specifically capture peptides/proteins bearing Phosphorylatedtyrosine residues but do not cross-react with the peptides/proteins bearing structurally similar Phosphorylatedserine or Phosphorylatedthreonine residues. This product has been well utilized to affinity purify peptides for global proteomic screening of tyrosine Phosphorylatedrylation.

IAP

Antibody

Research Use Only

Mix

Agarose

IgG

Tyrosine Phosphorylatedrylation is a fundamental biochemical process involving the addition of a phosphate group to the amino acid tyrosine within a protein. This modification represents one of the primary mechanisms of protein Phosphorylatedrylation. Tyrosine Phosphorylatedrylation holds significant importance in the realm of cell signaling transduction, playing a pivotal role in various pathophysiological conditions under the regulation of tyrosine kinase activities. In cancer, dysregulated tyrosine kinase activity can drive tumor malignancy and formation by generating inappropriate cell proliferation and survival signals. Antibodies that specifically target Phosphorylatedrylated tyrosine residues provide an exceptionally sensitive tool for investigating tyrosine Phosphorylatedrylation and its kinase activities in biomedical and preclinical studies.

Stable for 12 months from date of receipt.

All Species

All

Store at -20°C. Avoid freeze/thaw cycles.

12352203