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anti-PIM1 antibody

Research Use Only
ARG53469
Arigo Biolaboratories
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetPIM1
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-PIM1 antibody
  • Delivery Days Customer
    23
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID5292
  • Target name
    PIM1
  • Target description
    Pim-1 proto-oncogene, serine/threonine kinase
  • Target synonyms
    Oncogene PIM1; PIM; pim-1 oncogene (proviral integration site 1); proto-oncogene serine/threonine-protein kinase pim-1; serine/threonine-protein kinase pim-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203