anti-Pin 1 antibody
ARG10687
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityChicken
TargetPIN1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Pin 1 antibody
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5300
- Target namePIN1
- Target descriptionpeptidylprolyl cis/trans isomerase, NIMA-interacting 1
- Target synonymsDOD; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; PPIase Pin1; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; protein interacting with never in mitosis A1; rotamase Pin1; UBL5
- HostChicken
- IsotypeIgY
- Scientific DescriptionPeptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimers disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
- ReactivityChicken
- Storage Instruction-20°C
- UNSPSC12352203