anti-PLA2G4A phospho (Ser505) antibody

Arigo Biolaboratories

anti-PLA2G4A phospho (Ser505) antibody

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

PLA2G4A

phospholipase A2 group IVA

calcium-dependent phospholipid-binding protein; cPLA2; cPLA2-alpha; cytosolic phospholipase A2; GURDP; lysophospholipase; phosphatidylcholine 2-acylhydrolase; phospholipase A2, group IVA (cytosolic, calcium-dependent); PLA2G4

Rabbit

IgG

Phosphorylated

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

Human

-20°C

12352203