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Western blot analysis of protein glutamylation with MAb to polyglutamylation modification (GT335) (Prod. No. AG-20B-0020). Method: HeLa cells grown in standard culture conditions are lysed in SDS sample buffer and run on 10% SDS-PAGE. The pro
Western blot analysis of protein glutamylation with MAb to polyglutamylation modification (GT335) (Prod. No. AG-20B-0020). Method: HeLa cells grown in standard culture conditions are lysed in SDS sample buffer and run on 10% SDS-PAGE. The pro
Western blot analysis of protein glutamylation with MAb to polyglutamylation modification (GT335) (Prod. No. AG-20B-0020). Method: HeLa cells grown in standard culture conditions are lysed in SDS sample buffer and run on 10% SDS-PAGE. The pro

anti-Polyglutamylation Modification, mAb (GT335)

Research Use Only
AG-20B-0020
AdipoGen Life Sciences
ApplicationsElectron Microscopy, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityAll Species
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-Polyglutamylation Modification, mAb (GT335)
  • Delivery Days Customer
    10
  • Antibody Specificity
    Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin.
  • Applications
    Electron Microscopy, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT335
  • Concentration
    1 mg/ml
  • Estimated Purity
    >95%
  • Formulation
    Liquid
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Monoclonal Antibody. Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Isotype: Mouse IgG1kappa. Clone: GT335. Applications: EM, ICC, IHC, IP, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on the modified protein. It is evolutionarily conserved and the most prominent substrate is tubulin, the microtubule (MT) building block. Polyglutamylation has been proposed to be involved in the functional adaptation of MTs, as it occurs within the carboxy-terminal tubulin tails that participate directly in the binding of many structural and motor MT-associated proteins. The recent identification of new substrates of polyglutamylation indicates that this post-translational modification could be a potential regulator of diverse cellular processes and be involved in cell cycle and cell proliferation. - Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on the modified protein. It is evolutionarily conserved and the most prominent substrate is tubulin, the microtubule (MT) building block. Polyglutamylation has been proposed to be involved in the functional adaptation of MTs, as it occurs within the carboxy-terminal tubulin tails that participate directly in the binding of many structural and motor MT-associated proteins. The recent identification of new substrates of polyglutamylation indicates that this post-translational modification could be a potential regulator of diverse cellular processes and be involved in cell cycle and cell proliferation.
  • Reactivity
    All Species
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203

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