anti-PRAME antibody

Arigo Biolaboratories

anti-PRAME antibody

23

Western Blot

Research Use Only

Polyclonal

Unconjugated

PRAME

PRAME nuclear receptor transcriptional regulator

cancer/testis antigen 130; CT130; MAPE; melanoma antigen preferentially expressed in tumors; OIP4; OIP-4; opa-interacting protein 4; Opa-interacting protein OIP4; preferentially expressed antigen in melanoma; preferentially expressed antigen of melanoma

Rabbit

IgG

This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Human

-20°C

12352203