Anti-Propionyl-Histone H3 (Lys56) Rabbit mAb

PTM BIO

Anti-Propionyl-Histone H3 (Lys56) Rabbit mAb

5

Anti-Propionyl-Histone H3 (Lys56) Rabbit mAb detects histone H3 only when it is propionylated at Lys56

ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry Paraffin

WB, IHC-P, IP, ChIP

Antibody

Research Use Only

Monoclonal

PTM-012-5

Unconjugated

Rabbit

IgG

Histone H3.1

Histones are subject to a variety of enzyme catalyzed modifications, including acetylation, methylation, Phosphorylatedrylation, ubiquitylation, etc. Lysine propionylation (Kprop) is structurally similar to lysine acetylation, is a newly identified reversible modification controlling protein activity. Lysine propionylation is abundant in both prokaryotes and eukaryotes and has been found in wide ranges of proteins including histones and non-histone substrates, such as p53. Similar to acetylation of histone H4 at Lys5, propionylation of histone H4 at Lys5 may play a vital role in the epigenetic modulation, including chromatin remodeling and transcriptional regulation.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203