Anti-Propionyllysine Antibody Conjugated Agarose Beads

PTM BIO

Anti-Propionyllysine Antibody Conjugated Agarose Beads

5

With the immobilization of highly specific anti-propionyllysine antibody, the Anti-Propionyllysine Antibody Conjugated Agarose Beads selectively capture peptides/proteins bearing propionyllysine residues, but does not cross-react with the peptides/proteins bearing other structurally similar modified residues. This product has been well utilized to affinity purify peptides for global proteomic screening of lysine propionylation.

IAP

Antibody

Research Use Only

Mix

PA-024-15

Agarose

IgG

Propionylation of lysine, structurally similar to lysine acetylation, is a newly identified reversible modification controlling protein activity. The reversible lysine propionylation has been well demonstrated in both prokaryotes and eukaryotes in wide ranges of proteins including histones and non-histone substrates, such as p53. It is speculated that lysine propionylation plays a vital role in the regulation of multiple cellular processes including chromatin dynamics, plasticity, and DNA transcriptional regulation by sharing same regulative enzymes with lysine acetylation or with its unique regulative enzymes.

Stable for 12 months from date of receipt.

All Species

All

Store at -20°C. Avoid freeze/thaw cycles.

12352203