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Anti-Propionyllysine Mouse mAb

PTM-203
PTM BIO
ApplicationsWestern Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityAll Species
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Overview

  • Supplier
    PTM BIO
  • Product Name
    Anti-Propionyllysine Mouse mAb
  • Delivery Days Customer
    5
  • Antibody Specificity
    Anti- Propionyllysine Mouse mAb detects proteins with propionylated lysine residues. This pan antibody recognizes propionylated lysine independent of its surrounding sequences.
  • Applications
    Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry Paraffin
  • Applications Supplier
    WB, IHC-P, ChIP
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1300000
  • Conjugate
    Unconjugated
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    Propionylation of lysine, structurally similar to lysine acetylation, is a newly identified reversible modification controlling protein activity. The reversible lysine propionylation has been well demonstrated in both prokaryotes and eukaryotes in wide ranges of proteins including histones and non-histone substrates, such as p53. It is speculated that lysine propionylation plays a vital role in the regulation of multiple cellular processes including chromatin dynamics, plasticity, and DNA transcriptional regulation by sharing same regulative enzymes with lysine acetylation or with its unique regulative enzymes.
  • Shelf life instruction
    Stable for 12 months from date of receipt/reconstitution.
  • Reactivity
    All Species
  • Reactivity Supplier
    All
  • Reactivity Supplier Note
    Protein G and immunogen affinity purified
  • Storage Instruction
    Store at -20°C. Avoid freeze/thaw cycles.
  • UNSPSC
    12352203

References

  • LiuBingxin , et al. 'Severe fever with thrombocytopenia syndrome virus induces lactylation of m6A reader protein YTHDF1 to facilitate viral replication' EMBO REPORTS (2024)
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  • Wan Li, et al. 'Lactylation of RNA m6A demethylase ALKBH5 promotes innate immune response to DNA herpesviruses and mpox virus' PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2024)
    Read more