anti-Protein C antibody [HLW-C]

Arigo Biolaboratories

anti-Protein C antibody [HLW-C]

23

ELISA

Research Use Only

Monoclonal

HLW-C

1 mg/ml

Unconjugated

PROC

protein C, inactivator of coagulation factors Va and VIIIa

activated protein C; anticoagulant protein C; APC; autoprothrombin IIA; blood coagulation factor XIV; PC; prepro-protein C; PROC1; Protein C-Nagoya; THPH3; THPH4; type I protein C; vitamin K-dependent protein C

Mouse

IgG2b

Protein C is a vitamin K dependant glycoprotein in blood. Activated Protein C (APC) functions as an anti-coagulation factor in blood by proteolyzing pro-coagulation factors including Factor V and Factor VIII. When bound with endothelial protein C receptor (EPCR) on vascular endothelial cells, APC acts on protease activated receptor I (PAR-1) to up-regulate the expression of genes involved with anti-inflammatory and anti- apoptotic pathways, thus it also possesses a cell protective function. Protein C is activated by binding with thrombin. The activation is enhanced by thrombomodulin and EPCR.

Human

-20°C

12352203