Anti-Receptor tyrosine-protein kinase erbB-3 [BCD090-M2]

Absolute Antibody

Anti-Receptor tyrosine-protein kinase erbB-3 [BCD090-M2]

9

BCD090-M2 recognises erbB3, a receptor tyrosine kinase. The overexpression of erbB3 in breast cancers is associated with reduced survival in patients.

The crystal structure of BCD090-M2 has been obtained (Eliseev et al, 2018). SPR indicates the equilibrium dissociation constant for BCD090-M2 bound to immobilised erbB3 is 1 microm (Eliseev et al, 2018).

Other Application

Research Use Only

Monoclonal

BCD090-M2

ERBB3

erb-b2 receptor tyrosine kinase 3

c-erbB3; c-erbB-3; ErbB-3; erbB3-S; FERLK; HER3; human epidermal growth factor receptor 3; LCCS2; MDA-BF-1; p180-ErbB3; p45-sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; VSCN1

Mouse

IgG1

Receptor tyrosine-protein kinase erbB-3

This chimeric mouse antibody was made using a variable domain sequence of the original VHH format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203