anti-Retinoid X Receptor beta antibody [147]

Arigo Biolaboratories

anti-Retinoid X Receptor beta antibody [147]

23

Western Blot

Research Use Only

Monoclonal

147

Unconjugated

Rxrb

retinoid X receptor beta

AL023085; H-2R; H-2RIIBP; MHC class I regulatory element-binding protein H-2RIIBP; Nr2; Nr2b2; nuclear receptor subfamily 2 group B member 2; putative retinoid X receptor beta; RCo; RCoR-1; retinoic acid receptor RXR-beta; Ru; Rub

Mouse

IgG1

Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRalpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Mouse

-20°C

12352203