Flow Cytometry: Paraformaldehyde-fixed HeLa cells permeabilized with 0.5% Triton. Cells were stained with ARG63564 anti-RNF8 antibody (blue line) at 10 microg/ml dilution for 1 hour, followed by incubation with Alexa FluorR 488 labelled secondary antibody. IgG control: Unimmunized goat IgG (black line).
Flow Cytometry: Paraformaldehyde-fixed HeLa cells permeabilized with 0.5% Triton. Cells were stained with ARG63564 anti-RNF8 antibody (blue line) at 10 microg/ml dilution for 1 hour, followed by incubation with Alexa FluorR 488 labelled secondary antibody. IgG control: Unimmunized goat IgG (black line).
anti-RNF8 antibody
ARG63564
TargetRNF8
Product group Antibodies
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-RNF8 antibody
- Delivery Days Customer23
- Concentration0.5 mg/ml
- Gene ID9025
- Target nameRNF8
- Target descriptionring finger protein 8
- Target synonymsC3HC4-type zinc finger protein; E3 ubiquitin-protein ligase RNF8; hRNF8; ring finger protein (C3HC4 type) 8; ring finger protein 8, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase RNF8; UBC13/UEV-interacting ring finger protein
- Scientific DescriptionThe protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
- Storage Instruction-20°C
- UNSPSC12352203