anti-RNF8 antibody

Arigo Biolaboratories

anti-RNF8 antibody

23

Flow Cytometry, Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

RNF8

ring finger protein 8

C3HC4-type zinc finger protein; E3 ubiquitin-protein ligase RNF8; hRNF8; ring finger protein (C3HC4 type) 8; ring finger protein 8, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase RNF8; UBC13/UEV-interacting ring finger protein

Goat

IgG

The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Human

-20°C

12352203