Anti-Rt TCR alpha/beta Purified Low Endotoxin

EXBIO

Anti-Rt TCR alpha/beta Purified Low Endotoxin

7

The mouse monoclonal R73 recognizes an extracellular epitope TCR alpha/beta, the dominant subtype of T cell receptor expressed in peripheral blood.

Flow cytometry: Recommended dilution: 1-4 microg/ml. Functional application: In vitro activation and in vivo depletion of alpha/beta TCR T cells.

Functional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

R73

1 mg/ml

IgG1

The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.

Primate, Rat

2°C to 8°C

12352203