anti-Rubicon antibody
ARG23722
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetRUBCN
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Rubicon antibody
- Delivery Days Customer23
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9711
- Target nameRUBCN
- Target descriptionrubicon autophagy regulator
- Target synonymsbaron; beclin-1 associated RUN domain containing protein; KIAA0226; RUBICON; RUN and cysteine rich domain containing beclin 1 interacting protein; RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein; run domain Beclin-1-interacting and cysteine-rich domain-containing protein; rundataxin; SCAR15
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203