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anti-Rubicon antibody

ARG23722
Arigo Biolaboratories
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetRUBCN
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Rubicon antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9711
  • Target name
    RUBCN
  • Target description
    rubicon autophagy regulator
  • Target synonyms
    baron; beclin-1 associated RUN domain containing protein; KIAA0226; RUBICON; RUN and cysteine rich domain containing beclin 1 interacting protein; RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein; run domain Beclin-1-interacting and cysteine-rich domain-containing protein; rundataxin; SCAR15
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203