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Anti-RUNX2 Mouse mAb

Name: Anti-RUNX2 Mouse mAb
SKU: PTM-5253_P78
Availability: BackOrder

PTM-5253

ApplicationsWestern Blot

Product group Antibodies

Overview

Supplier
PTM BIO
Product Name
Anti-RUNX2 Mouse mAb
Delivery Days Customer
5
Applications
Western Blot
Applications Supplier
WB
Category Supplier
Antibody
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
10804
Conjugate
Unconjugated
Host
Mouse
Isotype
IgG
Protein IDQ13950
Protein Name
Runt-related transcription factor 2
Scientific Description
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1 collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.
Shelf life instruction
Stable for 12 months from date of receipt/reconstitution.
Reactivity Supplier
Mouse
Reactivity Supplier Note
Protein G purified
Storage Instruction
Store at -20°C. Avoid freeze/thaw cycles.
UNSPSC
12352203

Haibo Yao, et al. 'Whole-Transcriptome Sequencing of Antler Tissue Reveals That circRNA2829 Regulates Chondrocyte Proliferation and Differentiation via the miR-4286-R+1/FOXO4 Axis' INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
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