Anti-SARS-CoV-2 nucleocapsid [mBG86]

Absolute Antibody

Anti-SARS-CoV-2 nucleocapsid [mBG86]

9

mBG86 is specific to SARS-CoV-2 N protein and does not react with the SARS-CoV N protein or other similar N proteins (such as MERS-CoV, HuCoV-OC43, HuCoV-NL63, HuCoV-HKU1 and HuCoV-229E N). Western blot analysis with truncated fragments of N protein sugge

Specificty of the original mouse IgG1 version of this antibody to SARS-CoV-2 was confirmed by ELISA (Terry et al., 2021; pmid: 33714753). mBG86 is a particularly useful antibody as it can be used to detect SARS-Cov-2 N protein and differentiate it from SARS-CoV. Western blot analysis demonstrated that this antibody exhibits two band labeling, suggesting a specificity for conformational epitopes on the N protein (Terry et al., 2021; pmid: 33714753). This antibody was shown to detect SARS-CoV-2 N protein in methanol-stained Vero cells by immunofluorescence (Terry et al., 2021; pmid: 33714753). Finally, the original version of mBG86 was demonstrated to be an effective detection antibody in a sandwich ELISA assay suggesting its potential use in SARS-Cov-2 diagnostics (Terry et al., 2021; pmid: 33714753).

mBG86

N

nucleocapsid phosphoprotein

GU280_gp10; nucleocapsid phosphoprotein

Nucleoprotein

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

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