Anti-SARS-CoV S glycoprotein [A11]

Absolute Antibody

Anti-SARS-CoV S glycoprotein [A11]

9

This antibody specifically binds the epitope in the S2 domain of the spike protein in the region of Leu803-Ala828.

This antibody binds the amino acids Leu803-Ala828 in the S2 domain of the SARS-CoV. S2 domain mediates membrane fusion between the virus and the host cell. The binding specificity of antibody to S2b fragment of the viruse was checked by ELISA. Immunofluorescence staining was used to stain infected Vero cells using the A11-scFv. A11-scFv recognized recombinant spike protein S2-b during western blot analysis (Leung et al., 2008).

ImmunoFluorescence, Western Blot, ELISA

Research Use Only

Monoclonal

A11

Mouse

IgG2b

Spike glycoprotein

This full-length, chimeric mouse antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203