Anti-SARS-CoV S glycoprotein [F26G9]

Absolute Antibody

Anti-SARS-CoV S glycoprotein [F26G9]

9

This antibody specifically binds the amino acids 318-510 in the S1 domain of the SARS-CoV Spike protein. The originally characterized human IgG1 had a binding affinity of KD=10.2 (+/-3.5) nM.

This antibody is a SARS-CoV neutralizing antibody. F26G9 was capable of recognising both the S protein and the RBD in an ELISA. The neutralizing mAb, F26G9 specifically recognize SARS-HCoV infected but not uninfected Vero cells in immunofluorescence Immunofluorescence (Berry et al, 2004).

ImmunoFluorescence, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

F26G9

Human

IgG1

Spike glycoprotein

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203