Anti-SFTSV [B1G11 ], Human IgG1, Fc Silent(tm), kappa

Absolute Antibody

Anti-SFTSV [B1G11 ], Human IgG1, Fc Silent(tm), kappa

9

This antibody binds the severe fever and thrombocytopenic syndrome virus glycoprotein N. Severe Fever with Thrombocytopenia Syndrome (SFTS) is an emerging infectious disease caused by the SFTS virus which is transmitted to humans through the bite of an in

This antibody binds SFTSV glycoprotein N in a dose dependent manner in an ELISA. This antibody can be used to identify SFTSV Gn in a western blot. This antibody can also be used for immunofluorescence staining of SFTSV infected Vero cells. In vitro, this antibody is capable of neutralizing SFTSV-VSV pseudo-virus infected Vero cells. This antibody was also capable of neutralizing wild type virus infections for strains QD02 and WCH97 with an IC50 of 1.7microg/mL and 0.4microg/mL respectively (CN117964748).

ImmunoFluorescence, Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

B1G11

Human

IgG1

This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203