Anti-Shank3 [N69/46R]

Absolute Antibody

Anti-Shank3 [N69/46R]

7

This antibody is specific for the shank3. It shows no cross-reactivity against Shank1 or Shank2. Shank3 is a major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapsee f

This antibody was used for immunoblotting on hemibrains of wild-type, heterozygous and homozygous Shank3 mice (Bozdagi et al, 2010; PMID:21167025). hemibrains of wild-type, heterozygous and homozygous Shank3 rats were used for immunoblotting with this antibody (Harony-Nicolas et al, 2017; PMID:28139198). Half brains of mice were immunoblotted with this antibody (Kolevzon et al, 2010; PMID:21062623). Western blotting was preformed with this antibody on mouse tissue (Nikoletopoulou et al, 2017; PMID:28683289).

Western Blot

WB

Research Use Only

Monoclonal

N69/46R

Shank3

SH3 and multiple ankyrin repeat domains 3

proline-rich synapse-associated protein 2; Prosap2; SH3 and multiple ankyrin repeat domains protein 3; SH3/ankyrin domain gene 3; Shank postsynaptic density protein 3a; Spank-2

Mouse

IgG2a

SH3 and multiple ankyrin repeat domains protein 3

Human, Mouse, Rat

human, mouse, rat

This antibody was raised against synthetic peptide of amino acids 840-857 of rat Shank3.

-20°C,2°C to 8°C

12352203