Anti-Shiga toxin 1 [5-5B]

Absolute Antibody

Anti-Shiga toxin 1 [5-5B]

9

This antibody is specific for the Stx1 B subunit, and does not recognise Stx2

This antibody has been shown to bind the B subunit of Stx1 in Western blot analysis (Nakao et al, 2002). This antibody is able to neutralise Stx1 cytotoxicity (Nakao, 2002). Flow cytometric experiments have revealed that this antibody binds to free Stx1 B subunits, not cell-bound Stx1, and inhibits Stx1 binding to its receptor on target cells (Nakao et al, 2002). A Fab derived from this antibody also specifically binds Stx1, as determined by ELISA, and neutralises Stx1 cytotoxicity (Inoue et al, 2004).

Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

5-5B

Mouse

IgG1

Shiga toxin 1 B-subunit

Bacteria

-20°C,2°C to 8°C

12352203