Anti-Sigma1 [9BG5]

Absolute Antibody

Anti-Sigma1 [9BG5]

9

9BG5 was identified as a clone which significantly neutralised the strain T3D reovirus Sigma1 as assayed using viral titre of infection (Burstin et al, 1982). 9BG5 was able to immunoprecipitate strain T3D Sigma1, however some cross-reactivity was observed

9BG5 effectively neutralised reovirus strain T3D activity, and showed some inhibition of erythrocyte haemagglutination in virus-erythrocyte suspensions (Burstin et al, 1982). 9BG5 was also used to immunoprecipitate radiolabelled viral Sigma1 from L929 mouse fibroblast supernatants. More recently, 9BG5 was shown to cross-react with Sigma1 from the reovirus strain T1L, and contributed to blocking adherence of both T1L and T3D virions to CHO cells shown by flow cytometry (Dietrich et al, 2017).

Flow Cytometry, ImmunoPrecipitation, Other Application, RadioImmunoAssay

Research Use Only

Monoclonal

9BG5

Mouse

IgG2a

Virus

-20°C,2°C to 8°C

12352203