anti-SLC10A2 / ASBT antibody

Arigo Biolaboratories

anti-SLC10A2 / ASBT antibody

23

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

SLC10A2

solute carrier family 10 member 2

ASBT; IBAT; ileal apical sodium-dependent bile acid transporter; ileal sodium/bile acid cotransporter; ileal sodium-dependent bile acid transporter; ISBT; Na(+)-dependent ileal bile acid transporter; NTCP2; PBAM; PBAM1; sodium/taurocholate cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family), member 2; solute carrier family 10 (sodium/bile acid cotransporter), member 2

Goat

IgG

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]

Human

-20°C

12352203