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anti-SMC1A antibody (C-term)

Research Use Only
ARG54012
Arigo Biolaboratories
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetSMC1A
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-SMC1A antibody (C-term)
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Concentration
    2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8243
  • Target name
    SMC1A
  • Target description
    structural maintenance of chromosomes 1A
  • Target synonyms
    CDLS2; DEE85; DXS423E; EIEE85; epididymis secretory sperm binding protein; SB1.8; segregation of mitotic chromosomes 1; SMC protein 1A; SMC1; SMC1 (structural maintenance of chromosomes 1, yeast)-like 1; SMC1alpha; SMC-1-alpha; SMC1L1; SMCB; structural maintenance of chromosomes protein 1A
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203