Anti-SN-38 [1H3-1]

Absolute Antibody

Anti-SN-38 [1H3-1]

9

This antibody binds SN-38, which is an active metabolite of irinotecan (a semisynthetic analog of camptothecin - a topoisomerase I inhibitor) generated by carboxyl esterases through hydrolysis. SN-38 has potential antineoplastic activity. It binds and inh

The binding reactivity of this antibody to SN38-BSA conjugate was determined using ELISA. The binding affinity of this antibody to SN38-KLH conjugate was determined using surface plasmon resonance (SPR). It was reported that this antibody binds SN38-KLH conjugate with a binding affinity of Kd=3.06 nM (CN115197323).

ELISA, Other Application

Research Use Only

Monoclonal

1H3-1

Mouse

IgG2b

This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG2b format, created for improved compatibility with existing reagents, assays and techniques.

Other Species

-20°C,2°C to 8°C

12352203