anti-Staphylococcus Enterotoxin B antibody [SEB]

Arigo Biolaboratories

anti-Staphylococcus Enterotoxin B antibody [SEB]

23

ELISA

Research Use Only

Monoclonal

SEB

1 mg/ml

Unconjugated

seb

enterotoxin B

SACOL0907

Mouse

IgG1

Staphylococcal enterotoxin B (SEB) is an enterotoxin secreted by Staphylococcus aureus. The bacterium thrives on meet, baking and dairy products and also colonizes in host nasal passageway. Ingestion of SEB contaminated food is the common cause of food poisoning, manifested by flu-like symptoms, vomiting, diarrhea and intestinal cramps. In severe cases, SEB can cause respiratory failure and systemic toxic shock. These symptoms are the results of increased membrane permeability and abnormal activation of T-lymphocytes by SEB. SEB acts as a superantigen by binding directly to major histocompatibility complex class II (MHCII) on antigen presenting cells, thus, causing massive CD4 and CD8 T-cells activation and cytokine production. If unchecked, the process can result in systemic organ failure and death.

Bacteria

-20°C

12352203