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anti-Staphylococcus Enterotoxin B antibody [SEB]

ARG10080
Arigo Biolaboratories
ApplicationsELISA
Product group Antibodies
ReactivityBacteria
Targetseb
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Staphylococcus Enterotoxin B antibody [SEB]
  • Delivery Days Customer
    23
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SEB
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3237776
  • Target name
    seb
  • Target description
    enterotoxin B
  • Target synonyms
    SACOL0907
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Staphylococcal enterotoxin B (SEB) is an enterotoxin secreted by Staphylococcus aureus. The bacterium thrives on meet, baking and dairy products and also colonizes in host nasal passageway. Ingestion of SEB contaminated food is the common cause of food poisoning, manifested by flu-like symptoms, vomiting, diarrhea and intestinal cramps. In severe cases, SEB can cause respiratory failure and systemic toxic shock. These symptoms are the results of increased membrane permeability and abnormal activation of T-lymphocytes by SEB. SEB acts as a superantigen by binding directly to major histocompatibility complex class II (MHCII) on antigen presenting cells, thus, causing massive CD4 and CD8 T-cells activation and cytokine production. If unchecked, the process can result in systemic organ failure and death.
  • Reactivity
    Bacteria
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203