Anti-STAT3 phosphorylated [AbAb1-pSTAT3]

Absolute Antibody

Anti-STAT3 phosphorylated [AbAb1-pSTAT3]

9

This antibody binds human phosphorylated STAT3. This protein mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors.

The binding reactivity of this antibody to recombinant phosphorylated pSTAT3 peptide was confirmed using ELISA. The binding reactivity was further confirmed using western blot, of STAT3 protein IFN-alpha-treated cells. The scFv version of this antibody was used fused to human IgG1 using a suitable linker for the generation of scFv-Fc mini-antibody. This minibody was capable of immunoprecipitating pSTAT3 in the cell lysate of HeLa cells treated with IFN-alpha (US20090233358).

ImmunoPrecipitation, Western Blot, ELISA

Research Use Only

Monoclonal

AbAb1-pSTAT3

STAT3

signal transducer and activator of transcription 3

acute-phase response factor; ADMIO; ADMIO1; APRF; DNA-binding protein APRF; HIES; signal transducer and activator of transcription 3

Mouse

IgG2b

Signal transducer and activator of transcription 3

This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG format, created for improved compatibility with existing reagents, assays and techniques.

Human, Mouse

-20°C,2°C to 8°C

12352203