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Anti-Succinyllysine Antibody Conjugated Agarose Beads

PTM-402
PTM BIO
ReactivityAll Species
Product group Antibodies
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Overview

  • Supplier
    PTM BIO
  • Product Name
    Anti-Succinyllysine Antibody Conjugated Agarose Beads
  • Delivery Days Customer
    5
  • Antibody Specificity
    With the immobilization of highly specific anti-succinyllysine antibody, the Anti-Succinyllysine Antibody Conjugated Agarose Beads selectively capture peptides/proteins bearing succinyllysine residues, but do not cross-react with the peptides/proteins bearing other structurally similar modified residues. This product has been well utilized to affinity purify peptides for global proteomic screening of lysine succinylation.
  • Applications Supplier
    IAP
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Clonality
    Mix
  • Conjugate
    Agarose
  • Isotype
    IgG
  • Scientific Description
    Lysine succinylation is an important reversible modification, and plays significant roles i nmany cellular processes. Systematical screening of lysine succinylated substrates in various cellular pathological and physiological conditions is a fundamental mission in lysine succinylation biology.To address this,the affinity chromatography with Anti-Succinyllysine Antibody Conjugated Agarose Beads followed by MS/MS identification is viewed as the most preferable and efficient method.
  • Shelf life instruction
    Stable for 12 months from date of receipt.
  • Reactivity
    All Species
  • Reactivity Supplier
    All
  • Storage Instruction
    Store at -20°C. Avoid freeze/thaw cycles.
  • UNSPSC
    12352203

References

  • Shingo Takada, et al. 'Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure' PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)
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  • Li Lei, et al. 'SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability' Nature Communications (2016)
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  • Anderson Makayla Suzanne, et al. 'Succinyl-CoA Synthetase Deficiency in Mouse Forebrain Results in Hyper-Succinylation With Perturbed Neuronal Transcriptional Regulation and Metabolism' Cell Reports (2022)
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  • Yu Wang, et al. 'Lysine Succinylation of VBS Contributes to Sclerotia Development and Aflatoxin Biosynthesis in Aspergillus flavus' MOLECULAR & CELLULAR PROTEOMICS (2022)
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  • Gozde Colak, et al. 'Identification of Lysine Succinylation Substrates and the Succinylation Regulatory Enzyme CobB in Escherichia coli*' MOLECULAR & CELLULAR PROTEOMICS (2013)
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  • Lanxiang Liu, et al. 'Comprehensive analysis of the lysine acetylome and succinylome in the hippocampus of gut microbiota-dysbiosis mice' Journal of Advanced Research (2020)
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  • Juncheng Wang, et al. 'Global proteome analyses of phosphorylation and succinylation of barley root proteins in response to phosphate starvation and recovery' Frontiers in Plant Science (2022)
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  • Xiong Li, et al. 'Quantitative Succinyl-Proteome Profiling of Turnip (Brassica rapa var. rapa) in Response to Cadmium Stress' Cells (2022)
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  • Qianwen Ding, et al. 'Dietary Succinate Impacts the Nutritional Metabolism, Protein Succinylation and Gut Microbiota of Zebrafish' Frontiers in Nutrition (2022)
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  • Mingkun Yang, et al. 'Succinylome Analysis Reveals the Involvement of Lysine Succinylation in Metabolism in Pathogenic Mycobacterium tuberculosis' MOLECULAR & CELLULAR PROTEOMICS (2015)
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