Anti-Succinyllysine Antibody Conjugated Agarose Beads
PTM-402
ReactivityAll Species
Product group Antibodies
Overview
- SupplierPTM BIO
- Product NameAnti-Succinyllysine Antibody Conjugated Agarose Beads
- Delivery Days Customer5
- Antibody SpecificityWith the immobilization of highly specific anti-succinyllysine antibody, the Anti-Succinyllysine Antibody Conjugated Agarose Beads selectively capture peptides/proteins bearing succinyllysine residues, but do not cross-react with the peptides/proteins bearing other structurally similar modified residues. This product has been well utilized to affinity purify peptides for global proteomic screening of lysine succinylation.
- Applications SupplierIAP
- Category SupplierAntibody
- CertificationResearch Use Only
- ClonalityMix
- ConjugateAgarose
- IsotypeIgG
- Scientific DescriptionLysine succinylation is an important reversible modification, and plays significant roles i nmany cellular processes. Systematical screening of lysine succinylated substrates in various cellular pathological and physiological conditions is a fundamental mission in lysine succinylation biology.To address this,the affinity chromatography with Anti-Succinyllysine Antibody Conjugated Agarose Beads followed by MS/MS identification is viewed as the most preferable and efficient method.
- Shelf life instructionStable for 12 months from date of receipt.
- ReactivityAll Species
- Reactivity SupplierAll
- Storage InstructionStore at -20°C. Avoid freeze/thaw cycles.
- UNSPSC12352203
References
- Shingo Takada, et al. 'Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure' PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)Read more
- Li Lei, et al. 'SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability' Nature Communications (2016)Read more
- Anderson Makayla Suzanne, et al. 'Succinyl-CoA Synthetase Deficiency in Mouse Forebrain Results in Hyper-Succinylation With Perturbed Neuronal Transcriptional Regulation and Metabolism' Cell Reports (2022)Read more
- Yu Wang, et al. 'Lysine Succinylation of VBS Contributes to Sclerotia Development and Aflatoxin Biosynthesis in Aspergillus flavus' MOLECULAR & CELLULAR PROTEOMICS (2022)Read more
- Gozde Colak, et al. 'Identification of Lysine Succinylation Substrates and the Succinylation Regulatory Enzyme CobB in Escherichia coli*' MOLECULAR & CELLULAR PROTEOMICS (2013)Read more
- Lanxiang Liu, et al. 'Comprehensive analysis of the lysine acetylome and succinylome in the hippocampus of gut microbiota-dysbiosis mice' Journal of Advanced Research (2020)Read more
- Juncheng Wang, et al. 'Global proteome analyses of phosphorylation and succinylation of barley root proteins in response to phosphate starvation and recovery' Frontiers in Plant Science (2022)Read more
- Xiong Li, et al. 'Quantitative Succinyl-Proteome Profiling of Turnip (Brassica rapa var. rapa) in Response to Cadmium Stress' Cells (2022)Read more
- Qianwen Ding, et al. 'Dietary Succinate Impacts the Nutritional Metabolism, Protein Succinylation and Gut Microbiota of Zebrafish' Frontiers in Nutrition (2022)Read more
- Mingkun Yang, et al. 'Succinylome Analysis Reveals the Involvement of Lysine Succinylation in Metabolism in Pathogenic Mycobacterium tuberculosis' MOLECULAR & CELLULAR PROTEOMICS (2015)Read more