Anti-Succinyllysine Mouse mAb

PTM BIO

Anti-Succinyllysine Mouse mAb

5

Anti-Succinyllysine Mouse mAb detects proteins with succinylated lysine residues. This pan antibody recognizes succinylated lysine independent of its surrounding sequences.

Western Blot

WB

Antibody

Research Use Only

Monoclonal

3D3

Unconjugated

Mouse

IgG

Succinylation is a posttranslational modification where a succinyl group (-CO-CH2-CH2-CO2H) is added to a lysine residue of a protein molecule. This modification is found in many proteins, including histones. The potential role of succinylation is under investigation, but as addition of succinyl group changes lysine's charge from +1 to −1 (at physiological pH) and introduces a relatively large structural moiety (100 Da), bigger than acetylation (42 Da) or methylation (14 Da), it is expected to lead to more significant changes in protein structure and function.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Human, Mouse, Rat

Protein G and immunogen affinity purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203