Anti-Synphilin-1 (829-847)

Applied Biological Materials

Anti-Synphilin-1 (829-847)

9

A high level of specificity has been shown for this antiserum by IHC on human brain.

ImmunoHistoChemistry

Research Use Only

Polyclonal

1 ug/ul

Rabbit

Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shares a high level of identity with its human counterpart, particularly in regions containing ankyrin-like motifs and the coiled-coil domain. Expression pattern of synphilin-1 in tissues is similar in both mouse and human. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and also Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1.

Human, Rat

-20°C,2°C to 8°C

12352203