Anti-Thrombin [h1601-008], Human IgG1, kappa

Absolute Antibody

Anti-Thrombin [h1601-008], Human IgG1, kappa

9

This antibody is specific for human thrombin.

The original antibody was used for an ELISA on human thrombin to determine the binding activity. This antibody was used for surface plasmon resonance on human thrombin. The antibody showed good affinity. The effect of this antibody on thrombinase activity was determined. It showed that it did not inhibit the enzymatic activity of thrombin on substrate S2228. This antibody was used for a human plasma APTT test, it showed increasing APTT values with increasing antibody concentrations. This antibody was tested in vivo. The antibodies were administered to cynomolgus monkeys, they significantly inhibited the formation of thrombosis (US20190315886A1).

ELISA, Other Application

Research Use Only

Monoclonal

h1601-008

F2

coagulation factor II, thrombin

prepro-coagulation factor II; prothrombin; prothrombin B-chain; PT; RPRGL2; THPH1; thrombin factor II

Human

IgG1

Prothrombin

Human

-20°C,2°C to 8°C

12352203