Anti-Tim-4 [3A1]

Absolute Antibody

Anti-Tim-4 [3A1]

9

This antibody is specific for murine TIM-4. TIM-4, unlike other TIM family members, is not expressed on T lymphocytes but rather found on antigen-presenting cells such as lymphoid and myeloid dendritic cells and macrophages. TIM-4 has been shown to intera

The original version of this antibody (rat IgG1) specifically bound murine Tim-4 protein, as shown in ELISA and FC assays (Rodriguez-Manzanet et al., 2008; PMID: 18354194). This antibody can block apoptotic body (AB) recognition by CD11b+ peritoneal macrophages and partially inhibit AB uptake by peritoneal B-1 cells (Rodriguez-Manzanet et al., 2010; PMID: 20368430).

Flow Cytometry, ELISA

Research Use Only

Monoclonal

3A1

Timd4

T cell immunoglobulin and mucin domain containing 4

B430010N18Rik; smuckler; spleen, mucin-containing, knockout of lymphotoxin protein; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim; TIM-; Tim4; TIM-4; TIMD-4

Rat

IgG1

T-cell immunoglobulin and mucin domain-containing protein 4

Mouse

-20°C,2°C to 8°C

12352203