Anti-Tissue factor [5G9]
AB00516-1.1-BT
ApplicationsWestern Blot, ELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetF3
Overview
- SupplierAbsolute Antibody
- Product NameAnti-Tissue factor [5G9]
- Delivery Days Customer9
- Application Supplier NoteThe antibody binds specifically to TF, a hemostatic protein which is involved in the extrinsic pathway of coagulation. TF is receptor for circulating serine protease factor VIIa, activating the catalytic VIIa protease domain. The complex formed functions to activate the zymogen factor X into activated factor Xa, which then catalyses the formation of Prothrombin to Thrombin. The pathways results in a fibrin clot which acts to stop bleeding. The monoclonal antibody 5G9 acts as a competitive inhibitor of factor X, thereby inhibiting its activation by the TF.VIIa complex and the formation of a clot.
- ApplicationsWestern Blot, ELISA, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5G9
- Gene ID2152
- Target nameF3
- Target descriptioncoagulation factor III, tissue factor
- Target synonymsCD142; coagulation factor III (thromboplastin, tissue factor); TF; TFA; tissue factor
- HostMouse
- IsotypeIgG1
- Protein IDP13726
- Protein NameTissue factor
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203