Bio-Connect

Anti-Tissue factor [5G9]

AB00516-1.1-BT
Absolute Antibody
ApplicationsWestern Blot, ELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetF3
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-Tissue factor [5G9]
  • Delivery Days Customer
    9
  • Application Supplier Note
    The antibody binds specifically to TF, a hemostatic protein which is involved in the extrinsic pathway of coagulation. TF is receptor for circulating serine protease factor VIIa, activating the catalytic VIIa protease domain. The complex formed functions to activate the zymogen factor X into activated factor Xa, which then catalyses the formation of Prothrombin to Thrombin. The pathways results in a fibrin clot which acts to stop bleeding. The monoclonal antibody 5G9 acts as a competitive inhibitor of factor X, thereby inhibiting its activation by the TF.VIIa complex and the formation of a clot.
  • Applications
    Western Blot, ELISA, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    5G9
  • Gene ID2152
  • Target name
    F3
  • Target description
    coagulation factor III, tissue factor
  • Target synonyms
    CD142; coagulation factor III (thromboplastin, tissue factor); TF; TFA; tissue factor
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP13726
  • Protein Name
    Tissue factor
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203