Anti-Tissue factor [ATR-5]

Absolute Antibody

Anti-Tissue factor [ATR-5]

9

This antibody binds human tissue factor (TF) a hemostatic protein which is involved in the extrinsic pathway of coagulation. TF is receptor for circulating serine protease factor VIIa, activating the catalytic VIIa protease domain. The complex formed func

The binding of this antibody to human tissue factor expressed on the surface of human bladder carcinoma cells J82 was done using whole cell ELISA. This neutralizing activity of this antibody against the FX-binding was measured using the human placenta-derived thromboplastin. This antibody was also capable of inhibiting plasma coagulation (US6677436).

Functional Assay, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

ATR-5

F3

coagulation factor III, tissue factor

CD142; coagulation factor III (thromboplastin, tissue factor); TF; TFA; tissue factor

Rabbit

IgG

Tissue factor

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Human

-20°C,2°C to 8°C

12352203