anti-TL1A antibody
ARG66106
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetTNFSF15
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-TL1A antibody
- Delivery Days Customer23
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9966
- Target nameTNFSF15
- Target descriptionTNF superfamily member 15
- Target synonymsTL1; TL1A; TNF ligand-related molecule 1; TNF superfamily ligand TL1A; TNLG1B; tumor necrosis factor (ligand) superfamily, member 15; tumor necrosis factor ligand 1B; tumor necrosis factor ligand superfamily member 15; tumor necrosis factor superfamily member 15; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor-192A; VEGI; VEGI192A
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203