anti-TNFRSF18 antibody [DTA-1]
ARG56104
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
Product group Antibodies
ReactivityMouse
TargetTnfrsf18
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-TNFRSF18 antibody [DTA-1]
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDDTA-1
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID21936
- Target nameTnfrsf18
- Target descriptiontumor necrosis factor receptor superfamily, member 18
- Target synonymsAITR; Gi; Gitr; glucocorticoid-induced TNFR-related protein; tumor necrosis factor receptor superfamily member 18
- HostRat
- IsotypeIgG2b
- Scientific DescriptionThis gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
- ReactivityMouse
- Storage Instruction-20°C
- UNSPSC12352203