Anti-Transferrin

Applied Biological Materials

Anti-Transferrin

9

Research Use Only

Monoclonal

TRN

Mouse

IgA

When a transferrin protein loaded with iron encounters a transferrin receptor on the surface of a cell, e.g., erythroid precursors in the bone marrow, it binds to it and is transported into the cell in a vesicle by receptor-mediated endocytosis. The pH of the vesicle is reduced by hydrogen ion pumps (H+ATPases) to about 5.5, causing transferrin to release its iron ions.

-20°C,2°C to 8°C

12352203