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anti-TrkB antibody

ARG20177
Arigo Biolaboratories
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetNTRK2
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-TrkB antibody
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4915
  • Target name
    NTRK2
  • Target description
    neurotrophic receptor tyrosine kinase 2
  • Target synonyms
    BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; DEE58; EIEE58; GP145-TrkB; neurotrophic tyrosine kinase receptor type 2; OBHD; TRKB; trk-B; tropomyosin-related kinase B; tyrosine kinase receptor B
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Due to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular weights of 140-145 kDa, 110 kDa and the unglycosylated form of 80 kDa. trkB contains 33.3% carbohydrate by weight representing modification on 10 of 12 N-glycosylation sites. The primary ligand for trkB is BDNF which induces the phosphorylation of the protein and subsequent binding of PLC-gamma via SH2 domains. TrkB may function to modulate neuronal responses to the neurotrophins acting through trkB such as BDNF.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203