anti-TrkB antibody

Arigo Biolaboratories

anti-TrkB antibody

23

Western Blot

Research Use Only

Polyclonal

Unconjugated

Ntrk2

neurotrophic receptor tyrosine kinase 2

BDNF/NT-3 growth factors receptor; GP145-TrkB/GP95-TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; RATTRKB1; Tkrb; trkB; trk-B; trkB tyrosine kinase; TRKB1

Rabbit

IgG

Tropomyosin-receptor-kinase (TRK) receptors are members of the receptor tyrosine kinase family and include TrkA, TrkB and TrkC. Each of these receptor types has different binding affinities to the neurotrophins nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT-3). TrkB has the highest affinity to binding BDNF which plays critical roles in the function and survival of neurons in the CNS (Soppet et al., 1991; Klein et al., 1991). Additionally, alterations in expression of TrkB have been associated with Alzheimers disease (Ferrer et al., 1999; Chen et al., 2008).

Rat

-20°C

12352203