anti-TYK2 phospho (Tyr1054) antibody

Arigo Biolaboratories

anti-TYK2 phospho (Tyr1054) antibody

23

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

TYK2

tyrosine kinase 2

IMD35; JTK1; non-receptor tyrosine-protein kinase TYK2

Rabbit

IgG

Phosphorylated

TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Human

-20°C

12352203