Anti-TYK2 (Phospho-Tyr1054)

Applied Biological Materials

Anti-TYK2 (Phospho-Tyr1054)

9

TYK2 (phospho-Tyr1054) antibody detects endogenous levels of TYK2 only when phosphorylated at tyrosine 1054.

Western Blot

Research Use Only

Polyclonal

Rabbit

IgG

Phosphorylated

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]

Human, Mouse

-20°C,2°C to 8°C

12352203