anti-UBE2K antibody

Arigo Biolaboratories

anti-UBE2K antibody

23

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

UBE2K

ubiquitin conjugating enzyme E2 K

E2-25K, HIP2, HYPG, LIG, UBC1, ubiquitin-conjugating enzyme E2 K, E2 ubiquitin-conjugating enzyme K, E2(25K), HIP-2, huntingtin-interacting protein 2, ubiquitin carrier protein, ubiquitin conjugating enzyme E2K, ubiquitin-conjugating enzyme E2(25K), ubiquitin-conjugating enzyme E2-25 KDA, ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast), ubiquitin-protein ligase

Goat

IgG

The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntingtons disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

-20°C

12352203