Anti-VASP (Phospho-Ser157)

Applied Biological Materials

Anti-VASP (Phospho-Ser157)

9

VASP (phospho-Ser157) antibody detects endogenous levels of VASP only when phosphorylated at serine 157.

Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 ug/ul

Rabbit

Phosphorylated

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

-20°C,2°C to 8°C

12352203