Anti-VEGF [2H1], scFv fragment (His), ScFv,

Absolute Antibody

Anti-VEGF [2H1], scFv fragment (His), ScFv,

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This amtibody is specific for the human VEGF protein.

The original antibody was used for surface plasmon resonance on VEGF. This showed the binding affinity of the antibody to its antigen. This antibody was tested in vitro. It was assessed in a VEGF-stimulated HUVEC mitogenesis, it showed it was able to inhibit HUVEC proliferation in a dose dependent matter. This antibody was used for inhibition of VEGF-KDR binding. It showed that it was able to inhibit the binding. This antibody was used for an ELISA on different peptides of its antigen to determine its epitope (Lamdan et al., 2011; PMID:21167224, Lamdan et al., 2013; PMID:23702826).

ELISA, Other Application

Research Use Only

Monoclonal

2H1

This is a reformatted human scFv antibody, based on the original human scFv format, created for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203