Anti-VP28 [Mab 216]

Absolute Antibody

Anti-VP28 [Mab 216]

9

This antibody binds the VP28 envelope protein of the White spot syndrome virus (WSSV). White spot syndrome virus (WSSV) is a major pathogen in shrimp aquaculture. VP28 is one of the most important envelope proteins of WSSV.

This antibody was capable of detecting VP28 protein of WSSV in a western blot. Immuno-electron microscopy further showed that the epitope of this antibody is located on the viral envelope protein. In vitro neutralization studies in shrimp primary lymphoid cell culture showed diminished infectivity. In vivo neutralization assay showed 80% survival in shrimps injected with WSSV at a dilution of 1 x 10-3 pre-incubated with purified immunoglobulin (IgG) version of MAb 216. At higher virus concentration this antibody was not able to neutralize the virus (K.D.T. Natividad et al., 2007).

Western Blot, Neutralisation/Blocking

Research Use Only

Monoclonal

Mab 216

Rabbit

IgG

Virus

-20°C,2°C to 8°C

12352203